Thank you!
Your email is being processed.
You purchased this item on
View this order
Methylation support; Cellular energy production; Neurological health; DNA synthesis
Adults who prefer the active form of folate for daily methylation support and those with limited dietary folate intake.
Take 1 tablet once daily with a meal; taking with food may enhance tolerance.
Vegetarian, Vegan, Kosher, HALAL, Non-GMO; Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut, or sesame ingredients; Produced in a GMP facility that processes other allergens.
5-MTHF is the active folate form that donates methyl groups for one-carbon metabolism, supporting DNA synthesis, normal cell division, and methylation processes involved in neurotransmitter production.
Caution: If vitamin B12 status is low, high folate intake may hide signs of B12 deficiency, so adults with possible low B12 should monitor B12 levels; consult a healthcare professional if using certain medications like methotrexate or anti-seizure drugs due to potential interactions.
Label Warning: For adults only. Older adults and those with conditions that may impair vitamin B12 absorption should check vitamin B12 status, as high-dose folate may mask vitamin B12 deficiency. Consult a physician if pregnant or nursing, taking medications (especially phenobarbital, phenytoin, primidone, or methotrexate), or have a medical condition (especially any condition involving nutrient malabsorption).
Who should be cautious: People with a history of vitamin B12 deficiency, anemia of unclear cause, or nutrient malabsorption concerns may need extra caution. Those using anticonvulsants or methotrexate should discuss use with a healthcare provider before starting.
Storage: Store in a cool, dry place after opening.
Many users mention feeling more energetic after adding this methyl folate.
Small tablets are commonly described as simple to take daily.
A few users with specific needs mentioned mixed experiences despite the positive feedback.
This product is guaranteed authentic and backed by our easy returns & refunds policy. Details
Vitamin B12 and folate work together to support energy production and red blood cell formation, which may help maintain overall vitality and well-being.
AI generated. Not medical advice.
Sorry, there was a problem adding this item to cart. Please refresh the page and try again.
Methylfolate is the biologically active, naturally occurring form of folate that is used for fundamental body functions like normal cell division and the synthesis of neurotransmitters and DNA. Unlike regular folic acid, Methylfolate has been shown to penetrate the blood-brain barrier, where it helps to support neurological health. Quatrefolic® is a patented form of Methylfolate that has demonstrated bioavailability superior to that of folic acid from dietary sources.
Take 1 tablet daily with a meal.
Microcrystalline, cellulose, stearic acid (vegetable source) and silicon dioxide.
Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
For adults only. The elderly and individuals with conditions that may impair vitamin B-12 absorption should frequently check vitamin B-12 status when taking this product as high-dose folic acid may mask vitamin B-12 deficiency. Consult physician if pregnant/nursing, taking medication (especially phenobarbital, phenytoin, primidone, and methotrexate), or have a medical condition (especially any condition involving nutrient malabsorption). Keep out of reach of children.
Store in a cool, dry place after opening.
While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by iHerb.
| Supplement facts | ||
| Serving Size: 1 Tablet | ||
| Amount Per Serving | % Daily Value | |
| Folate [from Quatrefolic® (6S)-5-MTHF** Glucosamine Salt] | 1,700 mcg DFE [1,000 mcg (6s)-5MTHF**] | 425% |
| **MTHF = Methyltetrahydrofolate | ||
